Repeatability and reliability of the results of diffusion-weighted magnetic resonance imaging data analysis using mono-exponential, bi-exponential, and stretched exponential models for the assessment of liver properties in patients with early fibrosis and healthy volunteers

Prospective clinical trial of multimodal MRI quantitative parameters in early hepatic fibrosis

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2100052114

Enrollment

Unknown

Registered

2021-10-17

Start date

2020-05-01

Completion date

Unknown

Last updated

2022-06-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hepatic fibrosis

Interventions

Gold Standard:Pathological results of needle biopsy

Index test:Mono-exponential,&#32

Bi-exponential&#32

and&#32

Stretched&#32

exponential&#32

models&#32

of&#32

Diffusion-weighted&#32

Imaing

Eligibility

Sex/Gender

All

Age

21 Years to 62 Years

Inclusion criteria

Inclusion criteria: The pathological result was early hepatic fibrosis with mild hepatitis.

Exclusion criteria

Exclusion criteria: 1.Patients who had obtained pathological results from other hospitals before the experiment. 2.Patients with other malignant tumors or other diseases that may affect the experimental results. 3.Patients who are unable to complete relevant experimental results smoothly due to personal spirit or other reasons, or whose images are of poor quality and cannot be measured.

Design outcomes

Primary

Measure	Time frame
coefficient of variation;intra-class correlation coefficient;	—

Countries

China

Contacts

Public ContactTianzhu Liu

Guangdong Hospital of Traditional Chinese Medicine, Zhuhai

hadesfantasy012@21cn.com+86 13425022108

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026