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The effects of selective lobar lung isolation using a double endobronchial blocker technique in thoracoscopic lung surgery

The effects of selective lobar lung isolation using a double endobronchial blocker technique in thoracoscopic lung surgery

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100052086
Enrollment
Unknown
Registered
2021-10-16
Start date
2021-10-15
Completion date
Unknown
Last updated
2022-06-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thoracoscopic lung surgery

Interventions

Group A:Use a double endobronchial blocker technique
Group B:Use only one bronchial occluder

Sponsors

The Fourth Hosiptal of Hebei Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. ASA grade I-II; 2. Aged 18-65 years, body mass index (BMI) 18.5-25 kg/m^2; 3. No obvious abnormality in pulmonary function, FEV1/FVC% > 70%, unlimited or obstructive ventilatory dysfunction; 4. No obvious abnormality in cardiac function, no cardiovascular disease, ejection fraction (ejection fraction, EF) > 50%; 5. No preoperative anemia and other hematological diseases and no history of radiotherapy and chemotherapy; 7. Agree to participate in this study and sign an informed consent form.

Exclusion criteria

Exclusion criteria: 1. History of bronchial asthma and airway hyperreaction; 2. Patients with pulmonary infection, bronchopleural fistula, emphysema, pulmonary vesicles; 3. Those who could not complete the experiment after continuous one-lung ventilation for less than 1 hour; 4. Severe hypoxemia or other measures to improve oxygenation during operation; 5. Severe arrhythmia or death during or after operation; 6. There is a tumor in the airway, which affects the placement of double occluders.

Design outcomes

Primary

MeasureTime frame
Arterial blood gas analy;Incidence of hypoxemia (SpO2 < 92%);Classification of lung collapse;Postoperative pneumonia;Atelectasis;

Secondary

MeasureTime frame
The time of one lung ventilation;Surgeon satisfaction;The numbers of position change of endobronchial blocker;

Countries

China

Contacts

Public ContactFu Jianfeng

The Fourth Hosiptal of Hebei Medical University

fffjf2008@sohu.com+86 18531116090

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026