Postoperative pain treatment
Conditions
Interventions
Oxycodone group:Oxycodone 0.2 mg/kg
Sufentanil group:Sufentanil 0.2 ug/kg
Sponsors
The First Affiliated Hospital of Soochow University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Aged >= 18 years; 2. ASA I-III; 3. Scheduled to undergo laparoscopic major gastrointestinal surgery under general anesthesia (defined as duration of surgery >= 90 minutes, involving at least partial resection of the stomach or intestine).
Exclusion criteria
Exclusion criteria: 1. Emergency surgery; 2. Body mass index BMI >= 35 kg/m^2; 3. Allergy to the drug in the study; 4. Severe cardiopulmonary disease, severe cerebrovascular disease, severe liver and kidney disease (Child-Pugh C level, renal replacement therapy); 5. Severe neurological disease; 6. Preoperative cognitive impairment (MMSE score <= 23 points); 7. Use of antipsychotics; 8. Alcoholism; 9. Long-term opioid or other analgesic use; 10. Inability to understand pain rating scales; 11. Refuse to use patient-controlled intravenous analgesia (PCIA); 12. Written informed consent cannot be provided.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Visceral pain scores;Incisional pain scores;Shoulder pain scores;postoperative analgesic consumption;Overall patient satisfaction with analgesia;Sedation score;Nausea and vomiting;Use of antiemetics;Respiratory depression;Constipation;Dizziness; | — |
Primary
| Measure | Time frame |
|---|---|
| Visceral pain at rest during 1-24 h postoperatively;Visceral pain on coughing during 1-24 h postoperatively; | — |
Countries
China
Contacts
Public ContactPeng Ke
The First Affiliated Hospital of Soochow University
Outcome results
None listed