Clinical study of intracoronary esmolol in the treatment of reperfusion arrhythmia after acute myocardial infarction

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100052081

Enrollment

Unknown

Registered

2021-10-16

Start date

2022-01-01

Completion date

Unknown

Last updated

2022-06-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute myocardial infarction

Interventions

Experimental group:Esmolol and conventional treatment

Control group:Conventional treatment

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Patients diagnosed with acute anterior myocardial infarction who are to be treated with emergency PCI treatment; 2. Onset time is less than 12 hours; 3. Aged 18-85 years; 4. Those who voluntarily participated in this study and signed informed consent.

Exclusion criteria

Exclusion criteria: 1. History of bronchial asthma; 2. History of bradyarrhythmia; 3. Systolic blood pressure <= 90 mmHg; 4. Use of vasoactive drugs due to shock.

Design outcomes

Primary

Measure	Time frame
Arrhythmia;Echocardiography;Myocardial zymogram;	—

Secondary

Measure	Time frame
Blood pressure in consulting room;Heart rate;BNP(brain natriuretic peptide);Cardiopulmonary Exercise Testing;	—

Countries

China

Contacts

Public ContactGao Junqing

Shanghai Putuo District Central Hospital

kevingjq@sina.com+86 13816985971

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026