Stroke
Conditions
Interventions
Conventional rehabilitation group:On the basis of conventional treatment, the contralateral cerebral cortex was given sham stimulation
Single target stimulation group:On the basis of conventional rehabilitation, the contralateral cerebral cortex was given stimulation
Dual target stimulation group:On the basis of single target stimulation, Erbs point magnetic stimulation was added
Sponsors
Shanghai Tongji Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Patients diagnosed as stroke by clinical evaluation and comprehensive imaging examination meet the diagnostic criteria formulated by the 2014 National Cerebrovascular Academic Conference; 2. Fugl-Meyer motor function score proved to be motor dysfunction, and > 1 point in the combined movement evaluation project; 3. Aged 18-70 years, male or female; 4. No cognitive impairment or communication impairment, simple mental state examination (MMSE) more than 27 points; 5. The first onset, and the course of disease is from 2 days to 6 months.
Exclusion criteria
Exclusion criteria: 1. Those who have serious systemic diseases such as cardiopulmonary diseases and cannot tolerate rehabilitation treatment; 2. Patients diagnosed with psychosis, severe depression (suicidal tendency) or epilepsy, and family history of psychosis or epilepsy; 3. Patients with serious systemic diseases such as diabetes and uremia; 4. Patients with severe joint contracture; 5. Patients suffering from disturbance of consciousness for any reason; 6. According to the safety guidelines, there are contraindications for transcranial direct current/magnetic stimulation (TMS/tDCS) and functional magnetic resonance (fMRI), such as metal foreign bodies in the body or other electronic devices implanted in the body; 7. Hearing or visual defects may affect the evaluation and treatment; 8. Using drugs that change the excitability of cerebral cortex (antiepileptic drugs, sedative and hypnotic drugs, etc.).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fugl Meyer motor assessment(FMA); | — |
Secondary
| Measure | Time frame |
|---|---|
| MAS(Modified Ashworth Scale);MMT(Manual Muscle Test);Modified Barthel Index(MBI);Hand function assessment;Neuroelectrophysiological feedback and detection;fMRI(functional magnetic resonance imaging) brain function;fNIRS(functional near - infrared spectroscopy);EEG (electroencephalogram, resting EEG and evoked EEG); | — |
Countries
China
Contacts
Public ContactChen Yuhui
Shanghai Tongji Hospital
Outcome results
None listed