The efficacy of gastrointestinal stapled anastomosis with reinforeced seromuscular layer suture for reducing anastomotic leakage

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100052068

Enrollment

Unknown

Registered

2021-10-16

Start date

2022-01-01

Completion date

Unknown

Last updated

2022-06-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal carcinomas

Interventions

Reinforced anastomosis group:Stapled anastomosis of the digestive tract with reinforeced seromuscular layer suture

Nonreinforced anastomosis group:Stapled anastomosis of the digestive tract without reinforeced seromuscular layer suture

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1.The patient with resection of rectal cancer and prophylactic enterostomy for 3 to 12 months ago, and postoperative colonoscopy and colonography showed good healing of the rectal anastomosis; 2. The patient was 18 to 80 years old, and had no serious heart, lung, liver, kidney or coagulation dysfunction.

Exclusion criteria

Exclusion criteria: 1. Other contraindications for surgery; 2. Patients or authorized clients refuse to participate in clinical studies.

Design outcomes

Primary

Measure	Time frame
The incidence of postoperative anastomotic leakage and abdominal infection;	—

Secondary

Measure	Time frame
The operative time;Length of hospital stay;Hospitalization cost;Postoperative inflammatory indexes (such as blood routine, albumin, PCT, IL-6, etc.);	—

Countries

China

Contacts

Public ContactLi Zhigui

West China Hospital, Sichuan University

lizhigui07@sina.com+86 28 85422872

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026