Parkinson's disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Meet PD diagnostic criteria; 2. With salivation; 3. No patients with lung infection (the diagnostic criteria for pulmonary infection are based on the relevant diagnostic criteria in the Diagnostic Criteria for Nosocomial Infection: the clinical manifestations are mainly cough, difficult expectoration of sputum, shortness of breath, respiratory failure, etc.; the pathogen was positive); 4. Patients cooperated with treatment and signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Type A botulinum toxin is contraindicated, such as muscle weakness or botulinum toxin allergy; 2. There are serious primary diseases of other systems.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Salivation severity and frequency scale score;Salivation scale score for Parkinson's disease; | — |
Secondary
| Measure | Time frame |
|---|---|
| HAMD(Hamilton Depression Scale);HAMA(Hamilton Anxiety Scale);PDQ-39(Quality of Life Questionnaire for Parkinson's Disease);PDSS-2;Rosenberg self esteem scale; | — |
Countries
China
Contacts
The First Affiliated Hospital of Anhui University of Chinese Medicine