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Study on Predicting the Occurrence and Prognosis of Hypertensive Cerebral Hemorrhage by Using Plasma Trimethylamine-N-Oxide (TMAO)

Study on Predicting the Occurrence and Prognosis of Hypertensive Cerebral Hemorrhage by Using Plasma Trimethylamine-N-Oxide (TMAO)

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100052060
Enrollment
Unknown
Registered
2021-10-16
Start date
2022-01-01
Completion date
Unknown
Last updated
2022-06-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cerebral hemorrhage

Interventions

Control group:No
Cerebral hemorrhage group:Collect and analyze blood samples

Sponsors

The First Affiliated Hospital of Chengdu Medical College
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Cerebral hemorrhage group: 1. Clinical symptoms meet the diagnostic criteria for hypertensive cerebral hemorrhage; 2. Cerebral hemorrhage is clearly identified by CT or MRI, and the onset time is within 24 hours; 3. The clinical data of the patient is complete. Control group: subject who have a health checkup in this hospital during the same period.

Exclusion criteria

Exclusion criteria: Cerebral hemorrhage group: 1. Aged 2 points before onset; 3. Death within 24 hours; 4. No CT re-examination image data within 24 hours; 5. Artery Tumors, moyamoya disease and other diseases that may cause bleeding; 6. Have used antibiotics and probiotics within 1 month before bleeding; 7. Patients with a history of malignant tumors, autoimmune diseases, and immunosuppression. Control group: 1. Subject who have a history of infection and other acute diseases within 1 month; 2. Various cardiovascular and cerebrovascular diseases.

Design outcomes

Primary

MeasureTime frame
TMAO (Trimethylamine-N-Oxide);hs-CRP(hypersensitive-C-reactive-protein);Hcy (Homocysteine);National Institutes of Health Stroke Scale;Blood pressure;Glasgow Coma Scale;

Countries

China

Contacts

Public ContactYu Kai

The First Affiliated Hospital of Chengdu Medical College

yk18203410422@163.com+86 18203410422

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026