Cardiovascular diseases
Conditions
Interventions
Minimal right vertical infra-axillary thoracotomy group:Minimal right vertical infra-axillary thoracotomy
Mitral valve replacement with median sternal incision group:Mitral valve replacement with median sternal incision
Sponsors
Nanjing Drum Tower Hospital
Eligibility
Sex/Gender
All
Age
30 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Proposed mitral valve replacement; 2. There is no restriction on men and women, aged 30-70 years; 3. Sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Emergency surgery patients; 2. Other cardiac operations at the same time (congenital heart disease correction, coronary artery bypass grafting, large blood vessel surgery); 3. Coronary heart disease diagnosed by coronary angiography; 4. Have a history of cardiac or mediastinal surgery; 5. History of malignant tumors or infectious diseases; 6. Co-infection before surgery; 7. Thoracic deformity and other reasons are not suitable for chest surgery; 8. Preoperative liver and kidney dysfunction (EGFR 2; 10. NYHA >= III; 11. LVDD > 6.0 cm; 12. LVEF < 40%; 13. During pregnancy or lactation; 14. Combined immune system disease or connective tissue disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| All-cause mortality;Postoperative acute renal injury;Stroke;Surgery site infection;ARDS (acute respiratory distress syndrome);Severe arrhythmia;Valve-related reoperation rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative mechanical ventilation time;ICU(Intensive Care Unit) hospital stay;Total length of hospital stay; | — |
Countries
China
Contacts
Public ContactWang Dongjin
Nanjing Drum Tower Hospital
Outcome results
None listed