Diabetic macular edma
Conditions
Interventions
C-shape internal limiting membrane tear group:C-shape internal limiting membrane tear and cover the macular
Internal limiting membrane tear group:Internal limiting membrane tear
Sponsors
Eye Hospital and School of Ophthalmology and Optometry Affiliated to Wenzhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Aged >= 18 years; 2. Refractory DME: after 3-6 times of continuous anti-VEGF therapy and/or steroid therapy, OCT examination indicated that macular edema had no significant regression (regression was less than 10%); or after more than 6 anti-VEGF treatments, OCT examination suggested that anti-VEGF drugs were heavily dependent, and obvious macular edema occurred after drug withdrawal; 3. No posterior vitreous detachment was detected by B ultrasound and OCT; 4. Fundus examination/FFA examination confirmed diabetic retinopathy.
Exclusion criteria
Exclusion criteria: 1. Macular edema related to other diseases (retinal vein occlusion, uveitis, retinitis pigmentosa, cataract surgery, etc.); 2. Previous vitrectomy history; 3. OCT/OCTA suggested abnormal vitreous macular interface: macular premembrane, VMT; 4. Complicated with cataract, vitreous hematocele and other serious influence on fundus observation; 5. Cannot complete follow-up at the designated clinical trial center; 6. The presence of neurological or mental diseases can not cooperate with the examination; 7. Informed consent cannot be obtained.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Central macular thickness; | — |
Countries
China
Contacts
Public ContactWei Yong
Eye Hospital and School of Ophthalmology and Optometry Affiliated to Wenzhou Medical University
Outcome results
None listed