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Repetitive transcranial magnetism (rTMS) based on brain network in the treatment of depression and improvement of cognitive function: clinical randomized controlled study

Repetitive transcranial magnetism (rTMS) based on brain network in the treatment of depression and improvement of cognitive function: clinical randomized controlled study

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100052007
Enrollment
Unknown
Registered
2021-10-12
Start date
2021-10-18
Completion date
Unknown
Last updated
2022-06-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depression

Interventions

rTMS (repetitive transcranial magnetism) group:rTMS
Sham rTMS group:Sham rTMS
Control group:No

Sponsors

Ningbo Kangning Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Meet the diagnostic criteria of depression in the 10th Revision of the International Classification of Diseases (ICD-10) of diseases and related health problems; 2. Aged 18 to 65 years; 3. Right-handed; 4. The hospital ethics committee agreed, and the subjects signed an informed consent form.

Exclusion criteria

Exclusion criteria: 1. Patients with severe physical diseases, infectious diseases and immune system diseases; 2. Patients with severe neurological diseases, mental retardation or brain organic diseases; 3. Pregnant or breastfeeding women; 4. Receiving electricity within the past 3 months Shock therapy; 5. Have a history of electra convulsive therapy; 6. Those who are not suitable for rTMS or tDCS treatment after evaluation, and who cannot complete the collection of related indicators.

Design outcomes

Primary

MeasureTime frame
HAMD (Hamilton Depression Rating Scale) score;HAMA (Hamilton Rating Scale Anxiety) score;PSQI (Pittsburgh Sleep Quality Index) score;RBANS (Repeatable Battery for the Assessment of Neuropsychological Status) score;TAS (Toronto Alexithymia Scale);TMS-MEP (Transcranial Magnetic Stimulation Motor Evoked Potentials);TMS-EEG(Transcranial Magnetic Stimulation Electroencephalogram);fNlRs (Functional Near-Infrared Spectroscopy);rs-EEG (resting-state Electroencephalogram);ERP (Event Related Potentials);

Countries

China

Contacts

Public ContactZhou Dongsheng

Ningbo Kangning Hospital

wyzhouds@sina.com+86 574 26302520

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 9, 2026