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Efficacy and safety of Simiao pill for the prevention of hyperuricemia in suboptimal health status with dampness-heat syndrome

The ''inflammation-metabolism'' Crosstalk mechanism of intestinal microflora in subhealthy dampness-heat syndrome inducing blood uric acid increase and the intervention effect of Simiao pill

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100051995
Enrollment
Unknown
Registered
2021-10-12
Start date
2021-10-12
Completion date
Unknown
Last updated
2022-06-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

suboptimal health status

Interventions

Sponsors

Southern Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 30 Years

Inclusion criteria

Inclusion criteria: 1.In accordance with the diagnostic criteria of suboptimal health status, or conform to the diagnostic criteria of people of good health status; 2.Aged 18 to 30 years; male and female; 3.The subjects in suboptimal health status conforms to the western medicine clinical diagnosis standard of SHS; and conforms to the clinical syndrome diagnosis standard of damp heat syndrome in traditional Chinese medicine; 4.The subjects are informed and voluntarily signed the informed consent.

Exclusion criteria

Exclusion criteria: 1.Living with a serious adverse lifestyle; 2.With any infection in recent four weeks; 3.Pregnant or lactating women, or people who are allergic to the test drug; 4.Subjects who are taking part in other drugs clinical trials; 5.Volunteers whom researchers believe not suitable for the clinical trail with other reasons; 6.Family hereditary disease; 7.Antibiotics or microecological modulators were taken (or used) within two months before sampling.

Design outcomes

Primary

MeasureTime frame
Uric acid production and excretion;Dampness-heat syndrome score;

Secondary

MeasureTime frame
Health status score;Uric acid metabolism;Inflammatory factor-related indicators;Evaluation criteria of clinical syndrome efficacy;

Countries

China

Contacts

Public ContactZhao Xiaoshan

Southern Medical University

zhaoxs0609@163.com+86 18620277055

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026