The effect of oligosaccharide intervention on the intestinal microflora and development in preterm milk formula feeding preterm infants

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100051988

Enrollment

Unknown

Registered

2021-10-12

Start date

2018-01-01

Completion date

Unknown

Last updated

2022-06-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Growth and development of very preterm infants

Interventions

intervention group:Oligosaccharide-added formula

control group:Formulas without added oligosaccharides

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Inclusion criteria: gestational age at birth >28 weeks and <=32 weeks; complete data at birth and after birth; stable vital signs at enrollment; those who were still unable to breastfeed 2 weeks after birth and needed artificial feeding; stable clinical cardiopulmonary function at enrollment.

Exclusion criteria

Exclusion criteria: Exclusion criteria: congenital malformations; bruising congenital heart; genetic diseases; surgery required; premature infants who gave up treatment or died; patients with severe gastrointestinal dysfunction, cardiopulmonary dysfunction, and severe infection during the study.

Design outcomes

Primary

Measure	Time frame
intestinal microbiome;growth and development;immune function;	—

Countries

China

Contacts

Public ContactDefu Ma,Xiaomei Tong

Peking University

madefu@bjmu.edu.cn+86 010-82801743

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026