Skip to content

Effects of intermittent ? burst stimulation on social cognition and brain-derived neurotrophic factor in schizophrenia with metabolic syndrome

Effects of intermittent ? burst stimulation on social cognition and brain-derived neurotrophic factor in schizophrenia with metabolic syndrome

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100051984
Enrollment
Unknown
Registered
2021-10-11
Start date
2021-10-18
Completion date
Unknown
Last updated
2022-06-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Schizophrenia

Interventions

Experimental group:Really iTBS stimulation
Control group:Sham iTBS stimulation

Sponsors

Shanghai Pudong New Area Mental Health Center and Mental Health Center of Tongji University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1.Meet the ICD-10 diagnostic criteria for schizophrenia, and have no comorbidity with other mental illnesses; 2.Aged 18 to 65 years, gender is not limited; 3.Right-handed; 4.Antipsychotic drug treatment reaches full dose for at least two weeks; 5.Stable condition; 6.MS diagnosis adopts the joint transition statement criteria of the International Diabetes Federation Epidemiological Prevention Working Group in 2009.

Exclusion criteria

Exclusion criteria: 1.History of neurological disease; 2.Have a history of epilepsy; 3.Major physical disease; 4.Pregnant women; 5.Patients who have substance abuse or dependence 3 months before enrollment; 6.Have received rTMS treatment; 7.Are taking any anticonvulsant drugs.

Design outcomes

Primary

MeasureTime frame
Chinese emotional face recognition accuracy and use time;Metaphorical task score;Fasting insulin;

Secondary

MeasureTime frame
Serum brain derived neurotrophic factor concentration;Serum pro-brain derived neurotrophic factor concentration;Fasting plasma glucose;High density lipoprotein cholesterol;Low density lipoprotein cholesterin;Triglycerides;Glycated hemoglobin;Blood uric acid;

Countries

China

Contacts

Public ContactJin Ying

Shanghai Pudong New Area Mental Health Center and Mental Health Center of Tongji University

crystalkingying@163.com+86 18019780070

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 12, 2026