acute cerebral infarction
Conditions
Interventions
Experimental group:Acupuncture combined with intravascular intervention plus basic treatment
Control group:Intravascular intervention+basic treatment
Sponsors
Tianjin Huanhu Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Basic inclusion criteria: 1.Age >=18 years old; 2.The symptoms are consistent with acute ischemic stroke (onset time is 6-24 hours); 3.CTASPECT score >= 6, stroke severity score severe clinical deficits following physician evaluation, NIHSS >= 6 s; 4.The expected survival period is more than 6 months; 5.The patient or surrogate gave informed consent and was able to complete follow-up. Imaging inclusion criteria: 1.The infarct area is less than 1/3 of the blood supply area of the middle cerebral artery; 2.Diagnosed occlusion of the internal carotid artery (ICA) and/or the M1 segment of the middle cerebral artery (MCA-M1).
Exclusion criteria
Exclusion criteria: Basic exclusion criteria: 1.Patients with the modified Rankin Scale (MRS) greater than 2 points before the onset of this disease; 2.Patients with a history of contrast allergy or clear contraindications; 3.Patients with severe head injury and neurological dysfunction within 90 days; 4.The patients whose symptoms are relieved rapidly to NIHSS less than 6 points; 5.Patients with neurological or psychiatric disorders who have confused the judgment of the disease; 6.Patients with epilepsy who hinder the diagnosis of stroke and the judgment of neurological function; 7.Patients with blood glucose 22.20 mmol/L; 8.Patients with renal failure and creatinine > 264 µ mol/L; 9.Patients with bleeding tendency, coagulation factor deficiency, INR > 3.0 or PTT > 3 times normal in anticoagulation treatment; 10.Patients with platelet count 185 mmHg, diastolic blood pressure >110 mmHg in patients with uncontrolled hypertension; 12.Female pregnancy or lactation; 13.Patients with bacterial embolism or infective endocarditis. Imaging exclusion criteria: 1.Hemorrhagic stroke or large-scale ischemic stroke (the latter is defined as the infarct volume more than 1 / 3 of the middle cerebral artery blood supply area); 2.Carotid dissection; 3.Serious tortuosity of the carotid artery affecting the operation route; 4.Suspected vasculitis; 5.Suspected aortic dissection; 6.The occluded vessel had the influence of previous stent implantation on stent placement; 7.The infarct was in bilateral anterior circulation, such as bilateral carotid artery blood supply area; 8.Obvious occupying effect; 9.Intracranial tumor.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| National Institutes of Health Stroke Scale;Barthel index rating scale for daily living ability;Head Magnetic Resonance Imaging;Magnetic resonance imaging of cephalic vessels; | — |
Countries
China
Contacts
Public ContactZheng Na
Tianjin Huanhu Hospital
Outcome results
None listed