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Molecular mechanism of CIRC_PWWP2A regulating NLRP3 inflamma-somes in diabetic nephropathy

Molecular mechanism of CIRC_PWWP2A regulating NLRP3 inflamma-somes in diabetic nephropathy

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100051937
Enrollment
Unknown
Registered
2021-10-09
Start date
2021-11-01
Completion date
Unknown
Last updated
2022-06-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetic Nephropathy

Interventions

Control group:None
Type 2 diabetes without diabetic nephropathy group:None
T2DM with diabetic nephropathy group:No Intervention
Chronic kidney disease without diabetes:None

Sponsors

The Third Affiliated Hospital of Guangzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Diabetic nephropathy in type 2 diabetic patients, type 2 diabetic patients without diabetic nephropathy, chronic kidney disease patients without diabetes mellitus and healthy controls in our hospital.

Exclusion criteria

Exclusion criteria: 1.Patients have other causes of acute kidney injury; 2.Patients have haematology, immune system or tumor diseases.

Design outcomes

Primary

MeasureTime frame
circ-RAN;micro-RAN;protein and mRNA of NLRP3 inflammatory complex;inflammatory cytokine;endocrine metabolism indexes;urinary albumin;—

Countries

China

Contacts

Public ContactLi Renyuan

The Third Affiliated Hospital of Guangzhou Medical University

hi_ivy@163.com+86 18926146852

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026