Effect of intravenous lidocaine on EC50 of effective concentration of remifentanil in preventing tracheal extubation cough in female patients with thyroid surgery

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100051897

Enrollment

Unknown

Registered

2021-10-09

Start date

2021-10-10

Completion date

Unknown

Last updated

2022-06-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thyroid cancer

Interventions

Experimental group:Intravenous lidocaine

Control group:Intravenous saline

Eligibility

Sex/Gender

Female

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. ASA classification I-II; 2. Female; 3. Aged 18-65 years; 4. BMI<28 kg/m^2; 5. Elective thyroidectomy under general anesthesia with endotracheal intubation; 6. Sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. Those who are allergic to the active ingredients or any excipients related to the research; 2. History of abuse of sedative-hypnotics and painkillers; 3. Those with serious chronic diseases such as heart, liver and kidney; 4. History of chronic respiratory disease (such as chronic obstructive pulmonary disease or asthma), recent history of respiratory infection.

Design outcomes

Primary

Measure	Time frame
Severity of cough at extubation;	—

Countries

China

Contacts

Public ContactCai Hongda

Fujian Medical University

caihd@fjmu.edu.cn+86 13959137859

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026