The effects of an integrated supportive programme on xerostomia, salivary characteristics and oral health in patients with head and neck cancer undergoing radiotherapy: a randomized controlled trial

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100051876

Enrollment

Unknown

Registered

2021-10-08

Start date

2019-02-17

Completion date

Unknown

Last updated

2022-06-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Head and neck cancer

Interventions

Intervention group:Integrated supportive programme and usual care

Control group:Usual care

Eligibility

Sex/Gender

All

Age

23 Years to 66 Years

Inclusion criteria

Inclusion criteria: Patients with: a histological diagnosis of HNC; an age of 18 years or older; a Karnofsky Performance Scale Index (KPS) of 80-100; primarily received definitive RT for curative or surgery with postoperative RT for curative (dose of >= 60 grey) with concurrent or induction chemotherapy or both; and the ability to attend regular re-examination during the 12-month follow-up.

Exclusion criteria

Exclusion criteria: Patients with total edentulism; other cancer; other causes of xerostomia (i.e., Sjogren syndrome, diabetes mellitus, use of drugs that could interfere with salivary flow, removed bilateral salivary glands); or severe cognitive impairment (i.e., dementia) or psychiatric disorders that interfered with the ability to complete the questionnaire package.

Design outcomes

Primary

Measure	Time frame
Xerostomia Questionnaire;pH;Unstimulated salliva flow rate;buffering capacity;DMFT;Gingival index;Plaque index;OHIP-14;FACT H&N;WHO oral health survey for adults;	—

Countries

China

Contacts

Public ContactNan Jiang

Tianjin Medical University

nan.jiang@ju.se+86 15822773672

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 18, 2026