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Breast milk combined with sodium bicarbonate oral care to prevent ventilator-associated pneumonia in children with congenital heart disease surgery

Breast milk combined with sodium bicarbonate oral care to prevent ventilator-associated pneumonia in children with congenital heart disease surgery

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100051873
Enrollment
Unknown
Registered
2021-10-08
Start date
2021-09-27
Completion date
Unknown
Last updated
2022-06-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Heart disease

Interventions

Control group?:Use breast milk to scrub lips, cheeks, gums, hard palate, tongue, under tongue and the wall of the endotracheal tube, and swab each area with at least one cotton swab for at least 30 se
Control group?:Use sodium bicarbonate to scrub lips, cheeks, gums, hard palate, tongue, under tongue, and the wall of the endotracheal tube in turn, and scrub each part with at least one cotton swab f
Experimental group:Breast milk and 2.5% sodium bicarbonate solution were alternately used every 3 hours to scrub lips, cheeks, gums, hard palate, tongue, sublingual, and the wall of the endotracheal t

Sponsors

Fujian Medical University Union Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 1 Years

Inclusion criteria

Inclusion criteria: 1. Mechanically ventilated infants (<=1 year old) after cardiac surgery; 2. The patient was satisfied with the anatomical treatment, the postoperative cardiac function recovered well, and the hemodynamics was stable; 3. The mother of the child has sufficient breast milk.

Exclusion criteria

Exclusion criteria: 1. Patients with severe liver, kidney and other vital organ dysfunction; 2. Parents of patients who refuse to participate in this study; 3. Patients who drop out of the study halfway; 4. Patients who died during treatment.

Design outcomes

Primary

MeasureTime frame
Incidence of ventilator-associated pneumonia;Postoperative mechanical ventilation time;

Secondary

MeasureTime frame
Length of ICU stay;Postoperative hospital stay;Hospitalization expense;

Countries

China

Contacts

Public ContactLin Yanjuan

Fujian Medical University Union Hospital

fjxhyjl@163.com+86 591 86218336

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026