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Yunnan Baiyao Double-effect Anti-allergy Toothpaste in Relieving the Symptoms of Dentin Sensitivity: A Random Controlled Double-Blind Study

Yunnan Baiyao Double-effect Anti-allergy Toothpaste in Relieving the Symptoms of Dentin Sensitivity: A Random Controlled Double-Blind Study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100051869
Enrollment
Unknown
Registered
2021-10-08
Start date
2020-07-04
Completion date
Unknown
Last updated
2022-06-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dentin Hypersensitivity

Interventions

experimental group:Yunnan Baiyao double-effect antisensitivity toothpaste was used
control group:Use blank control toothpaste

Sponsors

West China Stomatological Hospital of Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Male or female subjects, aged 18-65 years. 2. Subjects who can continue to participate in the study within 8 weeks. 3. Subjects with at least two allergic teeth, including premolars or anterior teeth, with cervical abrasion or gingival recession. 4. Subjects with reaction readings of 10-30 g in the probe test (Yeaple probe). 5. The subjects with Schiff cold air sensitivity index of 2 or 3 were examined by air blowing method. 6. There are two teeth that are not in the same side of teeth arch, and the results of the above two examinations meet the reguirements 7. Subiects with good health were not allergic to the toothpaste. 8. Subjects who did not use desensitization toothpaste within 3 months before participating in the study. 9. Subjects willing to sign informed consent.

Exclusion criteria

Exclusion criteria: 1. Subjects with oral mucosal lesions, chronic diseases and allergic history to toothpaste components. 2. Subjects with periodontal disease progression or who have received periodontal treatment (including periodontal surgery) in the past year. 3. Subjects with more than I degree tooth mobility. 4. Subjects with extensive restoration, suspected pulpitis, caries, cracked enamel and removable partial denture. 5. Subjects taking anticonvulsants, antihistamines, antidepressants, sedatives, tranquilizers, anti-inflammatory agents and daily analgesics. 6. Subjects who participated in the study of desensitization toothpaste or daily use of desensitization toothpaste in the past 3 months. 7. Subjects who are participating in other clinical studies. 8. Female pregnancy or lactation. 9. Subjects with a history of allergy to personal health care products or their ingredients.

Design outcomes

Primary

MeasureTime frame
Tactile test;Airblast test;

Countries

China

Contacts

Public ContactWei Yin

West China Hospital of Stomatology

908069780@qq.com+86 13882208058

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026