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The effect of strict blood glucose management strategy on liver protection in liver transplantation: a prospective randomized controlled study

The effect of strict blood glucose management strategy on liver protection in liver transplantation: a prospective randomized controlled study

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100051868
Enrollment
Unknown
Registered
2021-10-08
Start date
2021-10-20
Completion date
Unknown
Last updated
2022-06-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

blood glucose management

Interventions

GRT group:Continuous dynamic glucose monitoring
Group C:Traditional arterial blood gas monitoring

Sponsors

Beijing Tsinghua Chunggung Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Aged > 18 years; 2. Orthotopic allogeneic liver transplantation is planned.

Exclusion criteria

Exclusion criteria: 1. MELD score > 30; 2. Complicated with severe cardiopulmonary disease; 3. Preoperative hemodynamic instability; 4. Preoperative life support (mechanical ventilation, renal replacement therapy, etc.); 5. Serious infection; 6. Allergy to anesthetics; 7. The patient refuses to participate in the study.

Design outcomes

Primary

MeasureTime frame
Surgical site infections;

Secondary

MeasureTime frame
Postoperative infection;New onset diabetes;Early graft dysfunction;Mean perioperative blood glucose;Perioperative blood glucose variability;Perioperative hypoglycemic events;Perioperative hyperglycemic events;Postoperative ICU length of stay;Length of postoperative hospital stay;Incidence of serious complications at 1 month after surgery;One-year survival rate;Liver function within 7 days after surgery;Inflammatory factor levels within 7 days after surgery;Postoperative delirium;

Countries

China

Contacts

Public ContactDuan Yi

Beijing Tsinghua Changgung Hospital

sunshine_duan@163.com+86 13810385311

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026