Grade 1 hypertension
Conditions
Interventions
Experimental group:Lingze Jiangya decoction combined with lifestyle intervention
Control group:Placebo combined with lifestyle intervention
Sponsors
Hainan Hospital of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. The blood pressure in the resting sitting consultation room before enrollment is 140-159/90-99 mm Hg, which is in line with the TCM diagnosis of excess liver-fire syndrome or excess phlegm-dampness syndrome; 2. Not taking antihypertensive drugs before, or taking the same antihypertensive drugs regularly in the past 2 weeks; 3. Aged 18-65 years, no gender limit; 4. No language and intellectual disability, can answer and fill in the questionnaire smoothly; 5. Sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Secondary hypertension; 2. Use of other drugs (excluding antihypertensive drugs) that affect blood pressure in the past month: such as hormone drugs, central nervous system drugs, non-steroidal anti-inflammatory drugs, etc.; 3. Patients diagnosed with senile hypertension, female menopausal hypertension, hypertension with diabetes, cerebrovascular disease, heart disease, kidney disease, peripheral vascular disease, and retinopathy; 4. Suspect or have a history of alcohol or drug abuse; 5. Those who are planning to become pregnant, patients of childbearing age who are not contraceptive, pregnant and lactating patients; 6. Patients who have participated in other clinical trials in the past 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes of systolic blood pressure in resting sitting consulting room compared with baseline (week 0) at week 12; | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes of systolic blood pressure in resting sitting room compared with baseline at other times;Changes of diastolic blood pressure in sitting room from baseline;Blood pressure control rate;Use of antihypertensive drugs;International physical activity questionnaire (IPAQ);Brief health status questionnaire 12 items (SF-12);TCM symptom score of hypertension; | — |
Countries
China
Contacts
Public ContactCheng Yawei
Hainan Hospital of Traditional Chinese Medicine
Outcome results
None listed