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A randomized controlled study comparing the efficacy of two bone marrow stimulation methods in the treatment of Hepple IV-V talar osteochondral injury

A randomized controlled study comparing the efficacy of two bone marrow stimulation methods in the treatment of Hepple IV-V talar osteochondral injury

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100051851
Enrollment
Unknown
Registered
2021-10-07
Start date
2021-10-20
Completion date
Unknown
Last updated
2022-06-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

osteochondral lesion of talus (OLT)

Interventions

Group 1:Subchondral drilling
Group 2:Microfracture

Sponsors

Peking University Third Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Focal ankle discomfort symptoms, which can be aggravated by exercise; 2. Single local OLT confirmed by X-ray or (and) MRI; 3. Hepple classification on MRI is in IV-V type; 4. Aged 18-60 years; 5. Cartilage injury diameter < 1.5 cm, area < 2.0 cm2 and depth < 0.5 cm; 6. Conservative treatment for 3 months has no obvious improvement.

Exclusion criteria

Exclusion criteria: 1. Bilateral ankle injury; 2. History of ankle fracture or other trauma and surgery in the past; 3. Combined with ankle muscle atrophy or ankle deformity and other neuromuscular diseases of the affected limb.

Design outcomes

Primary

MeasureTime frame
Cartilage Repair Tissue MR Observation Scoring System (MOCART) Score;—

Secondary

MeasureTime frame
American Orthopedic Foot & Ankle Society( AOFAS) Score;Visual Analog Rating Scale;Foot and Ankle Movement Score;—

Countries

China

Contacts

Public ContactJiang Dong

Peking University Third Hospital

bysyjiangdong@163.com+86 13811280948

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026