myopia
Conditions
Interventions
Experimental group:low-intensity red light therapy
Control group:high concentration of atropine
Sponsors
Shanghai General Hospital
Eligibility
Sex/Gender
All
Age
6 Years to 12 Years
Inclusion criteria
Inclusion criteria: 1. Aged 6-12 years; 2. School-age children who have developed myopia clinically diagnosed (after cycloplegia, check the binocular equivalent spherical lens -3.00D <= SE <= -1.00D, and the cylinder lens is <1.00D); 3. The best corrected visual acuity in one eye is 1.0 or above; 4. Parents agreed to random grouping and signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Have used low-concentration atropine eye drops (0.01%-0.5%) or high-concentration atropine eye drops (1%) in the past 3 months or children with myopia control such as orthokeratology lenses or multifocal/bifocal frame lenses; 2. Children with anisometropia (both eyes with diopter aberration >1.50D), strabismus, and amblyopia; 3. Secondary myopia (such as secondary myopia caused by retinopathy of prematurity or other eye diseases in infants and young children), or myopia combined with systemic syndrome (such as Marfan syndrome); 4. Children with photosensitivity and other major systemic diseases; 5. The refractive medium is cloudy (such as corneal disease, lens opacity, etc.); 6. Patients with retina, optic nerve, macular degeneration or other congenital and hereditary inner eye diseases; 7. Those with mental retardation, hyperactivity, etc. who cannot cooperate with treatment and follow-up; 8. Other reasons that the researcher considers unsuitable for inclusion in the project.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change of axial length (AL); | — |
Secondary
| Measure | Time frame |
|---|---|
| Change of uncorrected visual acuity (UCVA);Change of equivalent spherical refraction (SE);Change of corneal curvature;Change of white-to-white;Change of anterior chamber depth;Change of lens thickness;Change of sub-foveal choroidal thickness (SFChT);Changes of retinal and choroidal blood flow;Change of internal axial length (IAL);Time of outdoor activities; | — |
Countries
China
Contacts
Public ContactLu Yi
Shanghai General Hospital
Outcome results
None listed