small cell lung cancer
Conditions
Interventions
Experimental group:Low-dose radiotherapy plus immunotherapy
Sponsors
Jintang County First People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-75 years, no gender limit; 2. Histologically or cytologically confirmed small cell lung cancer; 3. Received prior two-line therapy for small-cell lung cancer; 4. Have at least one measurable lesion according to the efficacy evaluation criteria for solid tumors (RECIST 1.1); 5. ECOG: 0-2; 6. Expected survival >=12 weeks; 7. Subjects voluntarily joined the study and signed informed consent with good compliance and follow-up.
Exclusion criteria
Exclusion criteria: 1. Central nervous system metastasis with obvious symptoms; 2. The patient has any active autoimmune disease or has a history of autoimmune disease; 3. The patient has received more than 6 months of immunotherapy in the past; 4. There are contraindications to radiotherapy; 5. Patients with any severe and/or uncontrolled disease, including: patients with unsatisfactory blood pressure control (systolic blood pressure >= 150 mmHg or diastolic blood pressure >= 100 mmHg); suffering from myocardial ischemia or myocardial infarction above grade I, arrhythmia (including QT interval >=480ms) and grade I cardiac insufficiency; 6. Active or uncontrolled serious infection; 7. The researcher thinks that it is not suitable for inclusion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Objective response rate; | — |
Countries
China
Contacts
Public ContactZeng Yu
First People's Hospital of Jintang County
Outcome results
None listed