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Effects of transcutaneous electrical acupoint stimulation (TEAS) on postoperative gastrointestinal function and gut microbiome in patients undergoing spinal surgery

Effects of transcutaneous electrical acupoint stimulation (TEAS) on postoperative gastrointestinal function and gut microbiome in patients undergoing spinal surgery

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100051751
Enrollment
Unknown
Registered
2021-10-02
Start date
2021-10-18
Completion date
Unknown
Last updated
2022-11-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative gastrointestinal dysfunction

Interventions

Sham group (control group):Sham acupoints were selected for percutaneous electrical stimulation
Transcutaneous electrical acupoint stimulation (TEAS) group:ST36(Zusanli point), ST37(Shang Juxu point), ST39(Xia Juxu point), PC6(Neiguan point) and LI4 (Hegu point) were selected for bilateral percu

Sponsors

People's Liberation Army Joint Logistic Support Force 920th Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Lumbar fusion surgery; 2. BMI 18.5-28, aged 50-70 years, ASA grade I-III; 3. Operation duration >= 3 hours.

Exclusion criteria

Exclusion criteria: 1. Patients with previous diseases (diabetes, cerebral infarction, coronary heart disease, chronic kidney disease, nausea, tumor, hepatitis, cirrhosis, obesity, etc.); 2. Patients with preoperative malnutrition (nutritional assessment standard serum albumin AIB is the main, albumin < 35 g/L); 3. Preoperative anemia; 4. Preoperative gastrointestinal dysfunction; 5. There are skin infections; 6. Non-spinal surgery; 7. Abnormal coagulation; 8. Long-term use of drugs or recent use of antibiotics.

Design outcomes

Primary

MeasureTime frame
Time from the end of surgery to the start of normal bowel sounds (more than 2 sounds per time;The time to first flatus;The time to the first bowel;Duration of abdominal distention;Gene polymorphism analysis of intestinal flora;Severity of abdominal distention;

Secondary

MeasureTime frame
Serum midbrain intestinal peptide concentrations;Serum albumin;Nausea and vomiting score;VAS (visual analogue scale);Vasoactive intestinal peptide (VIP) concentrations;Cholecystokinin (CCK) concentrations;

Countries

China

Contacts

Public ContactLi Na

People's Liberation Army Joint Logistic Support Force 920th Hospital

45470739@qq.com+86 18687000606

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026