Lung injury
Conditions
Interventions
Traditional ventilation group:Conventional tidal volume ventilation (10-12 ml/kg)
Protective pulmonary ventilation group:Low tidal volume ventilation (6-8 ml/kg), positive end expiratory pressure 5 cmH2O and intermittent lung recruitment
Sponsors
Anhui Children's Hospital
Eligibility
Sex/Gender
All
Age
No minimum to 1 Years
Inclusion criteria
Inclusion criteria: 1. Patients who underwent exploratory laparotomy in Anhui children's Hospital; 2. Aged within 1 month, unlimited gender, body mass >= 2 kg; 3. ASA class II-III; 4. The estimated operation time is more than 1 hour.
Exclusion criteria
Exclusion criteria: 1. Those who refuse to participate in the experiment and do not sign the informed consent form; 2. Complicated with severe cardiovascular malformation; 3. Those with upper respiratory tract infection and obvious respiratory failure; 4. The general condition of the whole body is very poor.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Early postoperative pulmonary complications;Early postoperative inflammatory indexes; | — |
Secondary
| Measure | Time frame |
|---|---|
| Intraoperative ventilation parameters and oxygenation;Arterial blood gas;Postoperative hospital stay;Final outcome; | — |
Countries
China
Contacts
Public ContactChen Qi
The Second Hospital of Anhui Medical University
Outcome results
None listed