Sepsis
Conditions
Interventions
Sponsors
The First Affiliated Hospital of Dalian Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: Patients with sepsis or septic shock were included in the present study if they met the requirement of the third international consensus definitions for sepsis and septic shock (Sepsis-3), accompanied by sepsis-induced acute kidney injury (diagnosed according to the KDIGO clinical practice guidelines) with increase in serum creatinine of more than 300 µmol/L, oliguria (<100 mL/6 h) unresponsive to fluid resuscitation, severe acidemia of less than pH of 7.2, hyperkalemia of more than 6.5 mmol/L, or clinically significant organ edema (e.g., pulmonary edema).
Exclusion criteria
Exclusion criteria: Patients were excluded from the present study based on the following criteria: patients < 18 years old; patients with immunodeficiency virus infection, neutropenia (defined as an absolute neutrophil count of < 1,000 neutrophils/µL), acute bleeding, malignant tumor, pregnancy, or chronic kidney disease; patients who used corticosteroids or nephrotoxic drugs; patients who received any kind of renal replacement therapy prior to admission to the ICU; patients who refused to take part in the present study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| T Helper 1 Cells;T Helper 2 Cells;T Helper 17 Cells;T Regulatory cell; | — |
Countries
China
Contacts
Public ContactPing Gong
The First Affiliated Hospital of Dalian Medical University
Outcome results
None listed