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Clinical study of bronchial arterial infusion chemotherapy and PD-1 in the treatment of advanced lung squamous cell carcinoma

Clinical study of bronchial arterial infusion chemotherapy and PD-1 in the treatment of advanced lung squamous cell carcinoma

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100051533
Enrollment
Unknown
Registered
2021-09-26
Start date
2022-01-01
Completion date
Unknown
Last updated
2022-06-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung squamous cell carcinoma

Interventions

Experimental group:Arterial perfusion
The control group:Intravenous infusion

Sponsors

Chengdu Qingbaijiang District People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1. All patients were diagnosed with lung squamous cell carcinoma by clinicopathology, and the tumor stage of the patients were all stage III or IV, and the patients were unable or refused surgery, and the patients were unable or refused local radiotherapy; 2. Routine blood and biochemical tests are in line with drug use indicators, and there are no obvious abnormalities in important organs such as the heart, liver, and kidneys; 3. All patients are older than or equal to 18 years old; 4. The survival period of all patients is more than 6 months, and the KPS score is not lower than 70; 5. Non-pregnant and lactating women, subjects who have no pregnancy plan within 6 months after the trial (including male subjects); 6. The patient is conscious and has smooth communication; 7. All patients gave informed consent before participating in the study.

Exclusion criteria

Exclusion criteria: 1. Patients with other malignant tumors (except patients with lung cancer metastasis); 2. Those who have a history of mental illness in the past; 3. Patients who are allergic to immune drugs, chemotherapy drugs and contrast agents; 4. Pregnant or lactating women. 5. The perfusion area has normal tissues and organs that are sensitive to chemotherapy, such as the spinal cord.

Design outcomes

Primary

MeasureTime frame
Response Evaluation Criteria in solid tumors;

Countries

China

Contacts

Public ContactCao Lei

Chengdu Qingbaijiang District People's Hospital

327511253@qq.com+86 13880208081

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026