immunodeficiency due to autoantibody against interferon gamma
Conditions
Interventions
18-65 years old healthy control group:age
>65 healthy control group:age
Group of patients with other underlying chronic diseases:chronic disease
opportunistic infection group:opportunistic infections
Sponsors
The University of Hong Kong-Shenzhen Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1. Subjects: Patients aged >=18 years who were sent to the Department of Clinical Microbiology and Infection Control, The University of Hong Kong Shenzhen Hospital for testing from July 1, 2019 to June 30, 2021 were retrospectively retrieved and retrospectively reviewed. Detection of IFN-? autoantibodies; 2. Sample Size: At least 2000 samples will be tested. In addition to testing sera from patients with opportunistic infections that have been reported in our laboratory, samples from each of the following groups will be tested: (1) Healthy control group aged 18-65; (2) >65 healthy control group; (3) Patients with other underlying chronic diseases.
Exclusion criteria
Exclusion criteria: Unacceptable quality of archived sera sample.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| autoantibody against interferon gamma; | — |
Countries
China
Contacts
Public ContactXing Fanfan
The University of Hong Kong-Shenzhen Hospital
Outcome results
None listed