Brain stem hemorrhage
Conditions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients with primary brainstem hemorrhage: head CT showed that the hematoma was located in the pons, midbrain or medulla oblongata, the hematoma could rupture into the third or fourth ventricle, and may be accompanied by obstructive hydrocephalus. 2. Calculate the hematoma volume in the brainstem parenchyma by head CT (ABC calculation method, intraventricular hemorrhage is not included in the hemorrhage volume); 3. Glasgow coma score 3-8 on admission; the hematoma volume exceeds 3ml; 4. Time from onset to admission <= 48 hours; 5. The patient's aged 18 to 80 years; 6. Agree to accept the test and sign the consent form.
Exclusion criteria
Exclusion criteria: 1. Secondary brainstem hemorrhage caused by aneurysm, arteriovenous malformation, cavernous vascular malformation or tumor stroke was excluded by CTA or MRA; 2. Serious disorder of coagulation function; 3. Severe craniocerebral injury or intracerebral hemorrhage exceeding 30ml. 4. Patients with severe late brain herniation (bilateral mydriasis is fixed, no spontaneous breathing, and blood pressure is difficult to maintain); 5. The volume of hematoma in the brainstem parenchyma is less than 3ml or the GCS score at admission is more than 8 points; 6. Liver and kidney failure or combined with systemic malignant tumor; 7. History of mental disorder or neurological dysfunction in the past; 8. Patients with a history of cerebral hemorrhage; 9. Pregnant patients; 10. Patients who are participating in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| somatosensory;action; | — |
Countries
China
Contacts
Liaocheng People's Hospital