Application of goal-directed therapy based on VOT parameters in high-risk surgery

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100051494

Enrollment

Unknown

Registered

2021-09-24

Start date

2021-11-01

Completion date

Unknown

Last updated

2022-06-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Perioperative tissue hypoperfusion

Interventions

Experimental group:Goal-oriented therapy based on VOT parameters

Control group:Clinical routine anesthesia management

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Patients undergoing high-risk surgery under general anesthesia; (expected postoperative mortality greater than 5% is defined as high-risk surgery) 2. American Society of Anesthesiologists (ASA) classification II to IV; 3. Aged over 18 years old.

Exclusion criteria

Exclusion criteria: 1. Refuse to participate in this research; 2. Emergency surgery; 3. Neurological, cognitive or psychiatric disorders, including stroke with language impairment, dementia, and schizophrenia, or any condition that makes meaningful postoperative visits impossible; 4. Skin diseases that cannot tolerate non-invasive electrodes.

Design outcomes

Primary

Measure	Time frame
Lactic acid;Postoperative complication rate;scale scores of QoR-15;	—

Countries

China

Contacts

Public ContactZhang Chaofan

The First Affiliated Hospital of Zhengzhou University

zhangchaofan94@gmail.com+86 18625523328

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026