Perioperative neurocognitive disorders
Conditions
Interventions
Group PND:No
Group Non-PND:No
Sponsors
Dongguan Hospital Affiliated to Southern Medical University
Eligibility
Sex/Gender
All
Age
28 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. The patients aged 28 to 85 years ; 2. Complete clinical data; 3. ASA grades are I-II grades; 4. The surgical site is the abdomen (including stomach, colon, and rectal surgery); 5. Preoperative MMSE score > 26 points.
Exclusion criteria
Exclusion criteria: 1. Combined with uncontrollable diseases such as severe heart, liver and kidney dysfunction or malignant tumors; 2. Those with a history of neurological or mental illness; 3. Patients who take hypnotics, narcotic analgesics, antidepressants and anxiolytics for a long time; 4. Patients with coagulation disorders; 5. Poor compliance or unable to cooperate with the researcher due to other reasons.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| adiponectin;Cyclic adenosine monophosphate;proteinkinase A;Aquaporin 4;Phosphorylated Camp Response Element Binding Protein;brain-derived neurotrophic factor; | — |
Countries
China
Contacts
Public ContactXie Haihui
Dongguan Hospital Affiliated to Southern Medical University
Outcome results
None listed