Clinical and basic study on the effect of cisternostomy on the prognosis of patients undergoing decompression of large bone flap

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100051484

Enrollment

Unknown

Registered

2021-09-24

Start date

2021-12-01

Completion date

Unknown

Last updated

2022-06-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Severe craniocerebral injury, cerebral hemorrhage

Interventions

Experimental group:Conventional surgery+Cisternostomy

Control Group:Conventional surgery

Eligibility

Sex/Gender

All

Age

14 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Aged 14 to 70 years; 2. Patients with severe craniocerebral injury, cerebral hemorrhage, intracranial aneurysm, etc. who need standard decompression with large bone craniectomy.

Exclusion criteria

Exclusion criteria: Patients with bilateral cerebral herniation, patients with underlying diseases such as heart, lung, liver and kidney.

Design outcomes

Primary

Measure	Time frame
Glasgow result scoring;Severe edema rate;TNF-a;IL-6;APQ-4;MMP-9;	—

Secondary

Measure	Time frame
mortality rate;Postoperative infection rate;neonatal intensive care unit time;	—

Countries

China

Contacts

Public ContactSun Guoqing

Rizhao People's Hospital affiliated to Jining Medical College

13863338028@163.com+86 13863338028

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026