Clinical observation of continuous infusion of rimazolam methanesulfonate in patients with ICU mechanical ventilation

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100051478

Enrollment

Unknown

Registered

2021-09-24

Start date

2021-10-01

Completion date

Unknown

Last updated

2022-06-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sedation in patients with continuous mechanical ventilation

Interventions

Group 1:Remazolam tosylate

Group 2:Propofol

Group 3:Midazolam

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. ICU patients with mechanical ventilation and receiving sedation; 2. APACHE II score > 15 points; 3. Age >= 18 years old; 4. ICU stay > 24h; 5. All research subjects signed an informed consent form by themselves or their entrusted agents when they were admitted to the ICU; 6. Non-pregnant women and lactating women.

Exclusion criteria

Exclusion criteria: 1. Patients with neurological abnormalities or diseases; 2. Patients who are allergic to anesthesia and sedatives.

Design outcomes

Primary

Measure	Time frame
sedative effect;	—

Secondary

Measure	Time frame
safety;	—

Countries

China

Contacts

Public ContactXia Wenfang

Renmin Hospital of Wuhan University

59267089@qq.com+86 15972061317

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026