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The Research of MCP-1 and MMP-9 in the Formation of Pulmonary Bullae in Adolescent Spontaneous Pneumothorax

The Research of MCP-1 and MMP-9 in the Formation of Pulmonary Bullae in Adolescent Spontaneous Pneumothorax

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100051460
Enrollment
Unknown
Registered
2021-09-24
Start date
2020-12-01
Completion date
Unknown
Last updated
2022-06-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Spontaneous pneumothorax

Interventions

Pneumothorax case group :Nil
Non pneumothorax case control group:Nil

Sponsors

The Southern Yunnan Central Hospital of Yunnan (The First People's Hospital of Honghe)
Lead Sponsor

Eligibility

Sex/Gender
All
Age
14 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Inclusion criteria of pneumothorax subjects in case group: (1) Aged 80 points. (5) There were no chronic diseases such as hypertension, diabetes, coronary heart disease or hyperlipemia before operation. (6) No liver cirrhosis or other diseases affecting coagulation function before operation; (7) Preoperative cardiopulmonary function was good and compensatory ability was strong; (8) Informed consent. 2. Inclusion criteria of subjects with benign lung lesions in the control group: (1) Aged 80 points. (5) There were no chronic diseases such as hypertension, diabetes, coronary heart disease or hyperlipemia before operation. (6) No liver cirrhosis or other diseases affecting coagulation function before operation; (7) Preoperative cardiopulmonary function was good and compensatory ability was strong; (8) Informed consent.

Exclusion criteria

Exclusion criteria: (1) Over 60 years old, KPS score < 60; (2) Patients with severe cardiopulmonary disease; (3) Abnormal blood routine, liver and kidney function and coagulation function, with surgical contraindications; (4) Unexpected changes in the condition; (5) Patient had a history of mental illness and was unable to cooperate with the study.

Design outcomes

Primary

MeasureTime frame
macrophage count;percentage of elastic fiber;matrix metalloproteinase-9;monocyte chemoattractant protein-1;

Secondary

MeasureTime frame
age;sex;BMI;height;weight;

Countries

China

Contacts

Public ContactWang Sibo

The Southern Yunnan Central Hospital of Yunnan (The First People's Hospital of Honghe)

wangsibo86@126.com+86 18787360925

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 7, 2026