painless gastroscopy
Conditions
Interventions
Control group1:only remimazolam tosylate was used
Control group2:only propofol was used
Experimental group:remimazolam tosylate and propofol were given successively
Sponsors
The First People's Hospital of Jingzhou
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. The clinical data are accurate and complete, and patients who plan to undergo painless gastroscopy diagnosis and treatment; 2. Aged 18 to 60 years, BMI 18-28Kg/m2, ASA grade I-II; 3. No dysfunction of important organs such as heart, lung, liver and kidney, and no shock; 4. Have reading and comprehension skills, be informed about this research, and participate voluntarily.
Exclusion criteria
Exclusion criteria: 1. Patients with obvious respiratory and circulatory dysfunction and abnormal liver and kidney function before surgery; 2. Patients with severe neuropsychiatric diseases, long-term use of psychotropic drugs and cognitive dysfunction; 3. Those suffering from infectious diseases; 4. Those who have taken benzodiazepines or opioids intermittently every day within 1 month or within the past 3 months; 5. Those who are allergic or contraindicated to benzodiazepines, opioids, propofol, flumazenil, naloxone and other drugs and their components; 6. Obesity, OSAS and other patients who are judged to have difficulty in airway management: modified Markov score grade III and above; 7. History of drug abuse, and history of severe alcoholism; 8. Pregnant or breastfeeding women, or family planning within 3 months (including men); 9. Participate in any clinical trial within the past 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of perioperative adverse effects; | — |
Secondary
| Measure | Time frame |
|---|---|
| the induction time of sedation;time to alert;time to discharge; | — |
Countries
China
Contacts
Public ContactXia Rui
The First People's Hospital of Jingzhou
Outcome results
None listed