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Analysis of salivary gland damage in connective tissue disease

Analysis of salivary gland damage in connective tissue disease by radionuclide imaging

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100051445
Enrollment
Unknown
Registered
2021-09-23
Start date
2021-10-01
Completion date
Unknown
Last updated
2022-06-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

connective tissue disease

Interventions

Case series:None

Sponsors

Affiliated Stomatological Hospital of Nanjing Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. A clear diagnosis of connective tissue diseases (lupus erythematosus, rheumatoid arthritis, scleroderma, dermatomyositis, polyarteritis nodosa, Wegener's granulomatosis, giant cell arteritis, and Sj?gren's syndrome); 2. The patient consciously has obvious symptoms of dry mouth; 3. Within 1 month before and after diagnosis, use radionuclide dynamic imaging and static imaging to evaluate salivary gland function.

Exclusion criteria

Exclusion criteria: Exclude patients with overlap syndrome, other diseases of the systemic system, and acute infectious diseases of the salivary glands.

Design outcomes

Primary

MeasureTime frame
salivary gland volume;parotid gland uptake rate;submandibular gland uptake rate;parotid gland excretion rate;submandibular gland excretion rate;parotid gland perfusion rate;submandibular gland perfusion rate;peak time;—

Secondary

MeasureTime frame
20min/peak rate;20min/3min uptake rate;—

Countries

China

Contacts

Public ContactDu Hongming

Affiliated Stomatological Hospital of Nanjing Medical University

dhm_010@sina.com+86 17721508525

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026