Efficacy of low-molecular-weight heparin on improving pregnant outcomes in chronic endometritis negative after antibiotic treatment: a clinical validation

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100051442

Enrollment

Unknown

Registered

2021-09-23

Start date

2021-10-01

Completion date

Unknown

Last updated

2022-06-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic endometritis

Interventions

Experimental group:subcutaneous injection of low molecular weight heparin

Control group:NA

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1. Frozen-thawed blastocyst embryo transfer; 2. Chronic endometritis negative after antibiotic treatment, CD138 positive stroma cells counting less than 5/20HP; 3. Blastocyst grading: cavity fluid>=3, inner cell mass>=B, trophoblast cells >=B.

Exclusion criteria

Exclusion criteria: 1. Uterine submucosal fibroids; 2. Adenomyosis; 3. The intramural fibroids that compress the intimal line; 4. Endometrial polyps larger than 1 cm; 5. Intrauterine adhesions, uterine effusion.

Design outcomes

Primary

Measure	Time frame
clinical pregnancy rate;	—

Secondary

Measure	Time frame
early spontaneous abortion rate;	—

Countries

China

Contacts

Public ContactLi Yanping

Xiangya Hospital of Central South University

lisayanping@163.com+86 13607317798

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026