Duration of topical anesthesia and pain during intravitreal injection: a randomized controll clinical trial

Duration of topical anesthesia and pain during intravitreal injection

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100051435

Enrollment

Unknown

Registered

2021-09-23

Start date

2021-10-01

Completion date

Unknown

Last updated

2022-06-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Macula edema

Interventions

Experimental group1:5 minutes anesthesia duration before injection

Experimental group2:10 minutes anesthesia duration before injection

Experimental group3:15 minutes anesthesia duration before injection

Experimental group4:20 minutes anesthesia duration before injection

Experimental group5:25 minutes anesthesia duration before injection

Experimental group6:30 minutes anesthesia duration before injection

Experimental group7:35 minutes anesthesia duration before injection

Experimental group8:40 minutes anesthesia duration before injection

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Macular edema caused by various diseases; 2. The age is greater than or equal to 18 years old.

Exclusion criteria

Exclusion criteria: 1. Eye infections; 2. People with mental illness.

Design outcomes

Primary

Measure	Time frame
the visual analogue scale;Wong-Baker Facial Expression Scale scale;	—

Secondary

Measure	Time frame
best corrected visual acuity;Age;injection site;	—

Countries

China

Contacts

Public ContactMa Xiubin

Qingdao Eye Hospital affiliated to Shandong First Medical University

maxiubin2005@126.com+86 15864254696

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026