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Clinical risk factors for posttransplant diabetes in kidney transplantation patients using a tacrolimus-based triple immunosuppression regimen

Clinical risk factors for posttransplant diabetes in kidney transplantation patients using a tacrolimus-based triple immunosuppression regimen

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100051409
Enrollment
Unknown
Registered
2021-09-23
Start date
2021-09-14
Completion date
Unknown
Last updated
2022-06-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Kidney transplant

Interventions

Case series:None

Sponsors

The First Affiliated Hospital, Zhejiang University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Kidney transplant patients, age >=18 years; 2.Triple immunotherapy: tacrolimus + mycophenolate + glucocorticoid; 3.FK506 was taken orally on the second day after surgery, with an initial oral dose of 0.05-0.25 mg/(kg*d), divided into two oral doses, and the dosage was adjusted later according to blood concentration and other indications of patients.

Exclusion criteria

Exclusion criteria: 1.Patients who lost to follow-up; 2.Patients who discontinued tacrolimus after kidney transplantation for other reasons other than hyperglycemia; 3.Patients who failed to regularly monitor blood glucose and tacrolimus concentration data within 3 months after kidney transplantation; 4.A history of severe heart, lung, and liver sclerosis or malignancy.

Design outcomes

Primary

MeasureTime frame
New diabetes after transplantation;

Countries

China

Contacts

Public ContactHuang Mingzhu

The First Affiliated Hospital, Zhejiang University School of Medicine

hmzj2002@zju.edu.cn+86 87236675

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026