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The study of brain plasticity of acupuncture combined with antidepressants in the treatment of patients with moderate depression and insomnia comorbidities

The study of brain plasticity of acupuncture combined with antidepressants in the treatment of patients with moderate depression and insomnia comorbidities

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100051392
Enrollment
Unknown
Registered
2021-09-22
Start date
2021-10-01
Completion date
Unknown
Last updated
2022-06-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Comorbidity of depression and insomnia

Interventions

Group 2:Medication and acupuncture
Group 3:Medication and sham acupuncture

Sponsors

Dongguan Traditional Chinese Medicine Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: 1.Aged 18 to 50 years; 2.Meet the diagnostic criteria for depressive disorder in the DSM-V; 3.Mild depression, Hamilton Depression Scale score 7<HAMD-24<=17 points; 4.Pittsburgh sleep quality index(PSQI)score is more than 7; 5.Patients who have not received medical, physical or psychological treatment in the last three weeks; Or have been receiving medication and have maintained the original medication regimen for at least 3 weeks with stable condition; 6.Signed informed consent, voluntary participant.

Exclusion criteria

Exclusion criteria: 1.Past or present suicidal plan of self-injury or behavioral or psychotic symptoms; 2.History of schizophrenia, bipolar disorder or severe personality disorder; 3.Have an obvious history of personality disorders; 4.History of alcohol or substance abuse; 5.Previous history of brain trauma and epilepsy; 6.Patients with liver and kidney dysfunction, metal implants or major diseases of cardiovascular and cerebrovascular systems whose condition cannot be controlled; 7.May have poor compliance or fear acupuncture; 8.Left-handed 9.Women in pregnant or lactating.

Design outcomes

Secondary

MeasureTime frame
Self-Rating Depression Scale;Serum neuropeptide;

Primary

MeasureTime frame
Hamilton's Depression Scale;PSQI;

Countries

China

Contacts

Public ContactZhu Yu

Dongguan Traditional Chinese Medicine Hospital

zhuyuqiuzi@163.com+86 15202014631

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026