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Efficacy and safety of vital pulp therapy on carious pulp injury of permanent teeth: an open randomized controlled noninferiority study

Efficacy and safety of vital pulp therapy on carious pulp injury of permanent teeth: an open randomized controlled noninferiority study

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2100051369
Enrollment
Unknown
Registered
2021-09-21
Start date
2020-11-01
Completion date
Unknown
Last updated
2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

carious pulp injury of permanent teeth

Interventions

group of root canal treatment:root canal treatment

Sponsors

Hospital of Stomatology, Sun Yat-Sen University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Aged 18-50 years; 2. Permanent teeth with deep caries (class I or Class II cavities, with each wall thickness of the remaining tooth greater than 2mm); 3. Being diagnosed as reversible or partially irreversible pulpitis,without apical lucency on X-ray; 4. Without periodontitis or systemic disease. 5. Guangzhou resident population with good compliance and informed consent signed.

Exclusion criteria

Exclusion criteria: 1. Teeth with severe periodontitis, pulp calcification, root fracture or internal/external absorption; 2. Teeth with repairably large defect or having to get root canal treatment for aesthetic reasons. 3. Irreversible pulpitis or pulp necrosis; 4. Patients receiving orthodontic treatment; 5. Patients having systemic diseases and cannot bear the trial; 6. Patients under pregnancy; 7. Patients with bad compliance or could not complete the trial which is believed by investigators.

Design outcomes

Primary

MeasureTime frame
Duration of success;

Secondary

MeasureTime frame
success rate of one year;adverse reaction;

Countries

China

Contacts

Public ContactXi Wei

Hospital of Stomatology, Sun Yat-Sen University

weixi@mail.sysu.edu.cn+86 13602848822

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 5, 2026