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To explore the different expression of aqueous humor protein markers in different types of glaucoma

To explore the different expression of aqueous humor protein markers in different types of glaucoma

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100051358
Enrollment
Unknown
Registered
2021-09-21
Start date
2021-09-19
Completion date
Unknown
Last updated
2022-06-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

glaucoma

Interventions

Case series:None

Sponsors

Hainan Eye Hospital, Zhongshan Eye Center, Sun Yat-sen University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1.POAG is defined by basic surgical field of vision as (1)glaucoma neuropathology (GON); (2)characteristic field defects on the Humphrey field analyzer; (3) pre-ventricular Angle opening through GONIOSCOPY; (4)increased IOP> 21 mm HG of Goldmann Applanation Tonometer; 2.Pulmonary mite neuropathy (GON) is diagnosed if the cup/plate asymmetry > 0.2 is between the eye, marginal dilution, excision, excavation, excavation, or retinal nerve fibrous layer defects; 3.Characteristic fossil nodular visual field defects are the nasal cavity on the Bjerrum, Seidel, sub-detector or Humphrey visual field, in which clusters of 3 or more adjacent points suppress > 5dB or 2 adjacent points suppress > 10 dB.

Exclusion criteria

Exclusion criteria: 1.Subject has active eye infection or inflammation in either eye, such as active trachoma or endophthalmitis; 2.Subjects have eyelid or skin inflammation around the eyes, such as anterior blepharitis, atopic dermatitis, rosacea, spring catarrh conjunctivitis, etc.; 3.The subjects have eyelid abnormalities, such as entropion, ectropion, eyelid tumor, eyelid insufficiency, severe trichiasis, severe ptosis, etc.; 4.Subjects have previous severe corneal lesions, such as corneal chemical injury and corneal malnutrition; 5.Subjects have a history of eye surgery or trauma within 3 months prior to the examination; 6.The investigator judged that the subject could not comply with the study requirements.

Design outcomes

Primary

MeasureTime frame
Cytokine;

Countries

China

Contacts

Public ContactXu Li

Hainan Eye Hospital, Zhongshan Eye Center, Sun Yat-sen University

xuli-113@163.com+86 18789390190

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026