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Relationship between heterogeneity of weight loss and thyroid hormone in obese patients with type 2 diabetes mellitus treated with GLP1a

Relationship between heterogeneity of weight loss and thyroid hormone in obese patients with type 2 diabetes mellitus treated with GLP1a

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2100051350
Enrollment
Unknown
Registered
2021-09-21
Start date
2021-09-30
Completion date
Unknown
Last updated
2022-06-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 diabetes mellitus

Interventions

Weight gain group:None
Weight stability group:None

Sponsors

Tianjin Fourth Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1.Newly diagnosed type 2 diabetes patients in outpatients of our hospital, course of disease <=1 year; 2.Body mass index of 28kg/m^2; 3.Patients with normal thyroid function and treated with GLP-1a.

Exclusion criteria

Exclusion criteria: 1.Diagnosis of thyroid related diseases, such as hyperthyroidism, hypothyroidism, thyroid cancer and postoperative thyroid surgery; 2.Taking drugs that interfere with thyroid hormone (including glucocorticoid, levothyroxine sodium, antithyroid drugs, etc.) in the last 1 month; 3.Combined pregnancy or lactation; 4.Acute complications associated with diabetes mellitus; 5.Have a history of major cardiovascular and cerebrovascular diseases, chronic kidney disease and liver function impairment; 6.Sexually transmitted diseases such as viral hepatitis, AIDS and syphilis, and tuberculosis and other infectious diseases are in active stage; 7.History of malignant tumor; 8.Drug addicts.

Design outcomes

Primary

MeasureTime frame
thyrotropic hormone;free triiodothyronine;free thyroxine;weight;blood insulin;visceral fat;

Secondary

MeasureTime frame
triglyceride;

Countries

China

Contacts

Public ContactShao Hailin

Tianjin Fourth Central Hospital

shaohailin1988@sohu.com+86 22 26249403

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026