Effects of different vasoactive drugs on placental perfusion and neonatal adverse reactions

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100051326

Enrollment

Unknown

Registered

2021-09-20

Start date

2021-10-11

Completion date

Unknown

Last updated

2022-06-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obstetric patients

Interventions

Group A:Phenylephrine

Group B:Norepinephrine

Eligibility

Sex/Gender

Female

Age

18 Years to 40 Years

Inclusion criteria

Inclusion criteria: 1.ASA grade I-II; 2.Aged 18 to 40 years; 3.Primipara, term pregnancy, elective cesarean section.

Exclusion criteria

Exclusion criteria: 1.Hypertension (systolic blood pressure >140mmHg or diastolic blood pressure >90mmHg); 2.Heart disease; 3.Fetal abnormalities, placental abruption, placenta previa, abnormal fetal heart rate; 4.Contraindications to intraspinal anesthesia.

Design outcomes

Primary

Measure	Time frame
Umbilical arterial flow;	—

Secondary

Measure	Time frame
Blood pressure;The highest level of sensory block;Tachycardia, bradycardia incidence;	—

Countries

China

Contacts

Public ContactWang Tingting

Shanghai Changning Maternity and Infant Health Hospital

ti3wt@163.com+86 13564419229

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Sep 16, 2026