Feasibility Study of MR Guided Focused Ultrasound to Perform Central Lateral Thalamotomy for the Treatment of Chronic Neuropathic Pain

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2100051317

Enrollment

Unknown

Registered

2021-09-20

Start date

2021-10-01

Completion date

Unknown

Last updated

2022-06-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Neuropathic Pain

Interventions

treatment group: MR Guided Focused Ultrasound to Perform Central Lateral Thalamotomy

control group:MR Guided Focused Ultrasound without energy

Eligibility

Sex/Gender

All

Age

15 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Male and female, between the ages of 18 and 75 (inclusive); 2. Chronic neuropathic pain lasting >=6 months; 3. NPRS score >= 5 points (out of 10 points), the subject reported a similar degree of pain at least in the past two months; 4. Have taken at least 3 prescription drugs to relieve neuropathic pain, and currently use at least one drug; 5. Patients who are resistant to at least one intervention (including injections, surgery, neuromodulation, and surgery) or who are unable or unwilling to undergo such surgery.

Exclusion criteria

Exclusion criteria: 1. Craniofacial pain syndrome associated with head and neck cancer; 2. Idiopathic trigeminal neuralgia; 3. Migraine; 4. Atypical facial pain or pain associated with a somatoform disorder; 5. Subjects with active mental illness.

Design outcomes

Primary

Measure	Time frame
Numerical pain rating scale;	—

Countries

China

Contacts

Public ContactPan Longsheng

Department of Neurosurgery, First Medical Center, PLA General Hospital

panls301@163.com+86 13901365622

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026