diarrhoeal disease
Conditions
Interventions
acute diarrhea group:Nil
Sponsors
Children's Hospital of Zhejiang University School of Medicine
Eligibility
Sex/Gender
All
Age
No minimum to 18 Years
Inclusion criteria
Inclusion criteria: 1. The age is less than 18 years old; 2. Children diagnosed with diarrhea, including: (1) Acute diarrhea: infectious such as viral, bacterial, etc., non-infectious such as improper diet, climatic factors, etc.; (2) Persistent and chronic diarrhea; Including the following diseases: food allergies, food intolerance, indigestion, etc.; inflammatory bowel disease (IBD); diarrhea-type irritable bowel syndrome; antibiotic-associated diarrhea (AAD); other: chronic hepatitis related Diarrhea, metabolic disease-related diarrhea (such as diabetes with diarrhea, etc.), pancreatic exocrine dysfunction (cystic fibrosis), etc.; 3. Voluntarily participate in this study and sign the informed consent form or the guardian sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Class A infectious diseases associated with diarrhoea (cholera, plague) 2. Children with congenital heart disease, immune deficiency, malformation of digestive tract, or with severe dysfunction of heart, lung, liver and kidney 3. Children receiving long-term immunosuppressive therapy (except children with IBD) 4. Children with gastrointestinal surgery and tumor; 5. In addition to the above, the researchers determined that there were other children who were not suitable to participate in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The causes, clinical manifestations and clinical outcomes of diarrhoeal disease in children, including symptom remission rate and time to symptom remission, etc?; | — |
Secondary
| Measure | Time frame |
|---|---|
| Application distribution and efficacy of different treatment schemes in children with diarrhea;Oral rehydration, nutritional support and zinc supplementation;;The influencing factors of clinical effect included the demographic characteristics, clinical characteristics, combination regimen, etc;Clinical application of antibiotics;;Differences in therapeutic effects of different probiotics in children with diarrhea;;The dose, course, effectiveness and safety of Clostridium butyricum bivariate living agents in clinical application;;The medical cost of treatment of children's diarrhea medical resource consumption; | — |
Countries
China
Contacts
Public ContactJiang Mizu
Children's Hospital Affiliated to Zhejiang University
Outcome results
None listed