Intestinal microbiome and intestinal barrier function in Patients with Alzheimer's Disease

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2100051291

Enrollment

Unknown

Registered

2021-09-18

Start date

2021-09-16

Completion date

Unknown

Last updated

2022-05-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Alzheimer’s disease

Interventions

case series:no

Eligibility

Sex/Gender

All

Age

55 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. Aged 55-85 years; 2. Those who were diagnosed with Alzheimer's disease by the hospital were divided into mild dementia group and severe dementia group according to CDR score; 3. Have a clear mind and be able to cooperate to complete the entire test; 4. Sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. History of traumatic brain injury, cerebrovascular disease and other organic brain diseases; 2. Have a history of drug abuse or dependence; 3. Vascular dementia, mixed dementia, frontotemporal dementia, Lewy body dementia, Parkinson's dementia, paralytic dementia and other dementias; 4. History of mental disorders such as schizophrenia, senile depression, etc.; 5. Combined with serious heart, lung, liver, kidney, blood, endocrine and tumor diseases.

Design outcomes

Primary

Measure	Time frame
Intestinal microbiome;Intestinal barrier function;	—

Secondary

Measure	Time frame
clinical dementia rating;	—

Countries

China

Contacts

Public ContactWang Lei

Pla Rocket Force Characteristic Medical Center

hellowanglei068@163.com+86 18910883392

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026