Study on the correlation between postoperative cerebrospinal fluid and blood DLK content and prognosis in patients with aSAH

Study on the Role and Mechanism of NEK7/NLRP3 Signaling in Blood-Brain Barrier Injury after Subarachnoid Hemorrhage Based on Expression Profile Analysis

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2100051268

Enrollment

Unknown

Registered

2021-09-17

Start date

2020-05-01

Completion date

Unknown

Last updated

2022-08-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Subarachnoid hemorrhage

Interventions

aneurysmal subarachnoid hemorrhage group:Nil

spinal anesthesia patients without brain injury:Nil

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Male or female; 2. Aged >= 18 years; first attack case; 3. Confirmed aneurysmal subarachnoid hemorrhage and admitted to hospital within 72 hours after hemorrhage; 4. Patient/family members sign an informed consent form.

Exclusion criteria

Exclusion criteria: 1. Suspected pseudoaneurysm, previous neurological diseases such as transient ischemic attack, cerebral infarction, cerebral hemorrhage and multiple sclerosis took anticoagulant or anticoagulant drugs within one month before. 2. Accompanied by other comorbidities such as chronic heart, liver, kidney, lung and other diseases, malignant tumors.

Design outcomes

Primary

Measure	Time frame
mRS score;	—

Secondary

Measure	Time frame
WFNS score;	—

Countries

China

Contacts

Public ContactLiang Guobiao

Northern Theater General Hospital

liangguobiao6708@163.com+86 13898866708

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026